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Profusa Expands into Europe and Bitcoin, Joins Wall Street’s Digital Treasury Movement

From Spain to Satoshi: Health tech innovator taps $10.5B market while embracing Bitcoin like Strategy, MARA Holdings, and Trump Media.

Profusa (NASDAQ: PFSA), a rising player in digital health, just made two bold moves that caught the attention of investors in both the biotech and blockchain worlds. The California-based company announced a new European distribution deal for its Lumee™ Oxygen platform and confirmed an initial $1 million Bitcoin (BTCUSD) investment as the first step in a long-term digital asset treasury strategy.

Together, the two announcements mark a major inflection point for Profusa, a company aiming to disrupt real-time biochemical monitoring, while aligning itself with some of Wall Street’s most aggressive adopters of digital assets.

Profusa Targets $10.5B Oxygen Monitoring Market

On July 31, Profusa revealed that it signed a Letter of Intent with Spanish distributor Dismeval, S.L., securing access to hospitals and clinics across Spain, including the Canary and Balearic Islands. Dismeval’s experienced medical equipment team will distribute Profusa’s Lumee Oxygen platform, a real-time tissue oxygenation monitoring system designed to aid in managing peripheral artery disease, chronic wounds, and critical limb ischemia.

Profusa Chairman and CEO Ben Hwang, Ph.D., stated:

Establishing a distributor partner in Spain for our Lumee Oxygen platform is the first tangible step as we build a robust distribution infrastructure in Europe. We estimate a $10.5B+ global addressable market for our tissue oxygen technology across three indications – peripheral artery disease, chronic wounds, and critical limb ischemia.

With over 300,000 endovascular procedures performed annually in Europe alone, Profusa’s injectable biosensors and intelligent data platform could see substantial adoption. The company’s entrance into Spain sets the stage for broader EU expansion and greater clinical integration.

Profusa’s Lumee Oxygen Platform.
Source: jki.net/profusa

Profusa’s $1M Bitcoin Bet Signals Treasury Pivot

One day before the Spain deal, Profusa confirmed its initial $1 million Bitcoin investment under its newly initiated digital asset treasury strategy. The company partnered with BlockFills to execute the move and plans to expand its crypto holdings over time.

“This initial investment is an important first step in our collaboration with Ascent Partners Fund to establish a low-cost, capital-efficient, best-of-breed, Bitcoin treasury strategy reflecting our strong conviction in Bitcoin as the digital store of value for the future and our dedication to driving our healthcare programs forward,” said Hwang.

Profusa had already laid the groundwork for this crypto pivot with its July 21 announcement of a $100 million equity line of credit secured through a Securities Purchase Agreement with Ascent Partners Fund LLC. The proceeds will be allocated entirely to Bitcoin purchases, potentially for both reserve accumulation and debt repayment, provided that Profusa maintains a cash balance exceeding $5 million at the time of each transaction.

Hwang added:

As we continue on the journey to provide the best-in-class, AI-driven digital health platform for the benefit of chronic disease and health and wellness management, it is critical that we leverage opportunities to manage our resources to enable maximum shareholder value. In an era of accelerating monetary debasement, holding Bitcoin on our balance sheet represents a strategic move to safeguard shareholder value and align with a digital future.

Bitcoin Treasuries Explode Across Sectors

Profusa joins a booming movement that’s transforming idle corporate cash into crypto-powered assets. As of early August, public companies held over 791,000 BTC, nearly 4% of the total circulating supply, according to Galaxy Research. Treasury holdings have surpassed $100 billion, including contributions from digital health, mining, and fintech firms alike.

CleanSpark (NASDAQ: CLSK), Riot Platforms (NASDAQ: RIOT), and MARA Holdings (NASDAQ: MARA) anchor the mining contingent with tens of thousands of BTC each. Riot holds 19,225 BTC, while MARA’s 50,000 BTC stash ranks it just behind Strategy (NASDAQ: MSTR). Meanwhile, Galaxy Digital Holdings (NASDAQ: GLXY) has amassed 12,830 BTC as part of its diversified crypto finance strategy.

Trump Media & Technology Group (NASDAQ: DJT), the parent company of Truth Social and Truth+, entered the crypto fray with a splash, investing $2 billion in Bitcoin and related securities in July. That move vaulted DJT to one of the top-ten corporate Bitcoin holders, further legitimizing digital asset reserves as a financial strategy during Donald Trump’s second presidential term.

Beyond Bitcoin, Ethereum (ETHUSD) is rapidly emerging as the next major asset class for corporate balance sheets. BitMine Immersion (NYSE American: BMNR) now holds 625,000 ETH, alongside 172 BTC, and aims to become the “MicroStrategy of Ethereum.” BitMine plans to stake its ETH to generate additional yield, leveraging Ethereum’s unique staking model to actively grow its reserves.

Ethereum and Bitcoin in front of stock chart.
Source: Shutterstock

Altcoins Find Treasury Traction

Binance (BNBUSD) and Dogecoin (DOGEUSD) are also making their way into treasury portfolios. CEA Industries (NASDAQ: VAPE) recently announced a $500 million raise to accumulate BNB, following a 330% surge in share price. Meanwhile, Bit Origin (NASDAQ: BTOG) became the first publicly listed company to declare Dogecoin as its core treasury asset, purchasing over 40 million DOGE as part of a $500 million digital pivot.

KULR Technology Group (NYSE American: KULR), best known for its thermal and battery safety tech, also quietly added 1,021 BTC to its reserves, aligning with its innovation-focused identity and hedging against fiat volatility. Singapore’s BitFuFu (NASDAQ: FUFU) and US-based Cipher Mining (NASDAQ: CIFR) round out the mid-tier miners, each holding over 1,000 BTC.

Even outside the crypto-native sectors, treasury strategies are evolving. SharpLink Gaming (NASDAQ: SBET), best known for sports betting tech, holds sizable digital assets. And XXI (NASDAQ: CEP), also known as Twenty One Capital, has built a 37,230 BTC position in record time, valued near $5 billion.

Profusa: At the Crossroads of Health and Crypto

Profusa’s entrance into the digital treasury space marks a unique intersection of health tech and decentralized finance. Unlike many crypto-first firms, Profusa brings a strong foundation in biotech and real-world clinical applications. That background adds credibility to its decision to adopt Bitcoin, particularly as institutions increasingly frame crypto as a tool for risk management, not just speculation.

While its initial $1 million BTC position pales in comparison to the holdings of giants like Strategy or MARA Holdings, the company’s $100 million equity line of credit signals a long-term plan to scale its Bitcoin reserves significantly. And as Profusa continues to scale its Lumee Oxygen platform across Europe, it does so with a balance sheet that reflects both clinical ambition and financial innovation.

Whether Bitcoin hits $100K or Ethereum overtakes it in utility, one thing is certain: Profusa now has skin in the game, and it’s playing offense on two fronts.


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